Sequence Detail

ID/Version

Q924X7 Q4A1D4 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase 33 {ECO:0000305}; EC=2.7.11.1 {ECO:0000269|PubMed:37146716};

Provider

SWISS-PROT

Sequence

Polypeptide 491 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Stk33	serine/threonine kinase 33	33	101	3	13

Sequence references in MGI

J:71644 Amid C, et al., Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. Cytogenet Cell Genet. 2001;93(3-4):284-90
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:127635 Mujica AO, et al., Differential expression pattern of the novel serine/threonine kinase, STK33, in mice and men. FEBS J. 2005 Oct;272(19):4884-98
J:127636 Mujica AO, et al., A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3. Gene. 2001 Dec 12;280(1-2):175-81
J:177254 Brauksiepe B, et al., The Serine/threonine kinase Stk33 exhibits autophosphorylation and phosphorylates the intermediate filament protein Vimentin. BMC Biochem. 2008;9:25
J:253666 Martins LR, et al., Stk33 is required for spermatid differentiation and male fertility in mice. Dev Biol. 2018 Jan 1;433(1):84-93
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:352418 Yu W, et al., STK33 Phosphorylates Fibrous Sheath Protein AKAP3/4 to Regulate Sperm Flagella Assembly in Spermiogenesis. Mol Cell Proteomics. 2023 Jun;22(6):100564
J:352589 Ku AF, et al., Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science. 2024 May 24;384(6698):885-890