Sequence Detail

ID/Version

Q924A0 Q924A1 Q91XP2 Q9Z0V3 Q9Z0V4 Q91XP3 Q91XP4 O70574 Q8C834 (UniProt | EBI)

Last sequence update: 2003-03-25
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Transcription factor 7-like 2;AltName: Full=HMG box transcription factor 4;AltName: Full=T-cell-specific transcription factor 4; Short=T-cell factor 4; Short=TCF-4; Short=mTCF-4;

Provider

SWISS-PROT

Sequence

Polypeptide 459 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	129	179	3	39

Sequence references in MGI

J:45934 Korinek V, et al., Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. Mol Cell Biol. 1998 Mar;18(3):1248-56
J:48968 Korinek V, et al., Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet. 1998 Aug;19(4):379-83
J:52289 Lee YJ, et al., A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation. J Biol Chem. 1999 Jan 15;274(3):1566-72
J:72420 Douglas KR, et al., Identification of members of the Wnt signaling pathway in the embryonic pituitary gland. Mamm Genome. 2001 Nov;12(11):843-51
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:154695 Mahmoudi T, et al., The kinase TNIK is an essential activator of Wnt target genes. EMBO J. 2009 Nov 4;28(21):3329-40
J:176253 Vacik T, et al., A novel mechanism for the transcriptional regulation of Wnt signaling in development. Genes Dev. 2011 Sep 1;25(17):1783-95