Sequence Detail

ID/Version

Q91ZX6 Q811R3 Q544T8 Q9D4Z0 (UniProt | EBI)

Last sequence update: 2002-11-28
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Sentrin-specific protease 2 {ECO:0000305}; EC=3.4.22.- {ECO:0000269|PubMed:11489887, ECO:0000269|PubMed:20194620, ECO:0000269|PubMed:27637147};AltName: Full=Axam2 {ECO:0000303|PubMed:12419228};AltName: Full=SUMO-1 protease 1;

Provider

SWISS-PROT

Sequence

Polypeptide 588 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Senp2	SUMO/sentrin specific peptidase 2	56	107	3	28

Sequence references in MGI

J:84904 Best JL, et al., SUMO-1 protease-1 regulates gene transcription through PML. Mol Cell. 2002 Oct;10(4):843-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161702 Chung SS, et al., Control of adipogenesis by the SUMO-specific protease SENP2. Mol Cell Biol. 2010 May;30(9):2135-46
J:208907 Nishida T, et al., Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation. J Biol Chem. 2001 Oct 19;276(42):39060-6
J:259271 Hu MM, et al., Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus. Immunity. 2016 Sep 20;45(3):555-569
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89