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Sequence Detail
ID/Version
Q91ZW3 Q8CA22 Q8VDG1 Q8C791 Q925M9 (UniProt | EBI) Last sequence update: 2001-12-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; EC=3.6.4.- {ECO:0000250|UniProtKB:O60264};AltName: Full=Sucrose nonfermenting protein 2 homolog; Short=mSnf2h;
Provider SWISS-PROT
Sequence
Polypeptide 1051 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 82 114 3 16
Sequence references in MGI J:69527 Lazzaro MA, et al., Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l. J Neurochem. 2001 May;77(4):1145-56
J:71381 Strohner R, et al., NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines. EMBO J. 2001 Sep 3;20(17):4892-900
J:76488 Bozhenok L, et al., WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci. EMBO J. 2002 May 1;21(9):2231-41
J:79869 Santoro R, et al., The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. Nat Genet. 2002 Nov;32(3):393-6
J:86695 Stopka T, et al., The ISWI ATPase Snf2h is required for early mouse development. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14097-102
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:143888 Xiao A, et al., WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity. Nature. 2009 Jan 1;457(7225):57-62
J:150926 Zhou Y, et al., The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J. 2002 Sep 2;21(17):4632-40
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory