Sequence Detail

ID/Version

Q91ZU6 Q9WU50 Q8K5D4 Q3I6J6 E9QL23 Q1KP04 Q60845 S4R1U5 Q91ZU8 E9PXE5 Q91ZU7 Q60824 (UniProt | EBI)

Last sequence update: 2014-09-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Dystonin;AltName: Full=Bullous pemphigoid antigen 1; Short=BPA;AltName: Full=Dystonia musculorum protein;AltName: Full=Hemidesmosomal plaque protein;AltName: Full=Microtubule actin cross-linking factor 2;

Provider

SWISS-PROT

Sequence

Polypeptide 7393 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dst	dystonin	82	143	3	239

Sequence references in MGI

J:24974 Guo L, et al., Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration. Cell. 1995 Apr 21;81(2):233-43
J:26733 Brown A, et al., The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1. Nat Genet. 1995 Jul;10(3):301-6
J:35022 Yang Y, et al., An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments. Cell. 1996 Aug 23;86(4):655-65
J:52837 Leung CL, et al., The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons. J Cell Biol. 1999 Feb 8;144(3):435-46
J:55704 Dalpe G, et al., Dystonin-deficient mice exhibit an intrinsic muscle weakness and an instability of skeletal muscle cytoarchitecture. Dev Biol. 1999 Jun 15;210(2):367-80
J:56502 Yang Y, et al., Integrators of the cytoskeleton that stabilize microtubules. Cell. 1999 Jul 23;98(2):229-38
J:80762 Leung CL, et al., The BPAG1 locus: Alternative splicing produces multiple isoforms with distinct cytoskeletal linker domains, including predominant isoforms in neurons and muscles. J Cell Biol. 2001 Aug 20;154(4):691-7
J:86328 Liu JJ, et al., BPAG1n4 is essential for retrograde axonal transport in sensory neurons. J Cell Biol. 2003 Oct 27;163(2):223-9
J:86716 Young KG, et al., Bpag1 localization to actin filaments and to the nucleus is regulated by its N-terminus. J Cell Sci. 2003 Nov 15;116(Pt 22):4543-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104464 Young KG, et al., A Bpag1 isoform involved in cytoskeletal organization surrounding the nucleus. Exp Cell Res. 2006 Jan 15;312(2):121-34
J:119738 Liu JJ, et al., Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2223-8
J:139041 Young KG, et al., Dystonin/Bpag1 is a necessary endoplasmic reticulum/nuclear envelope protein in sensory neurons. Exp Cell Res. 2008 Sep 10;314(15):2750-61
J:156784 Steiner-Champliaud MF, et al., BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin. Exp Cell Res. 2010 Feb 1;316(3):297-313
J:158696 Boyer JG, et al., Hearts of Dystonia musculorum mice display normal morphological and histological features but show signs of cardiac stress. PLoS One. 2010;5(3):e9465
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89