Sequence Detail

ID/Version

Q91Z31 Q9R0V9 Q9CUW2 Q9QYC2 Q7TNW7 (UniProt | EBI)

Last sequence update: 2006-04-18
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Polypyrimidine tract-binding protein 2 {ECO:0000305};AltName: Full=Brain-enriched polypyrimidine tract-binding protein; Short=Brain-enriched PTB;AltName: Full=Neural polypyrimidine tract-binding protein;AltName: Full=RRM-type RNA-bin

Provider

SWISS-PROT

Sequence

Polypeptide 531 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptbp2	polypyrimidine tract binding protein 2	29	113	4	48

Sequence references in MGI

J:62658 Polydorides AD, et al., A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6350-5
J:68159 Lillevali K, et al., Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain. Mech Dev. 2001 Mar;101(1-2):217-20
J:87851 Rahman L, et al., Evolutionary conservation of a 2-kb intronic sequence flanking a tissue-specific alternative exon in the PTBP2 gene. Genomics. 2004 Jan;83(1):76-84
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:273745 Saito Y, et al., Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function. Neuron. 2019 Feb 20;101(4):707-720.e5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89