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Sequence Detail
ID/Version
Q91YM2 Q3UGY1 Q69ZC4 (UniProt | EBI) Last sequence update: 2007-01-09
Last annotation update: 2019-12-11
Sequence
description
from provider
RecName: Full=Rho GTPase-activating protein 35 {ECO:0000312|MGI:MGI:1929494};AltName: Full=Glucocorticoid receptor DNA-binding factor 1;
Provider SWISS-PROT
Sequence
Polypeptide 1499 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Arhgap35 Rho GTPase activating protein 35 48 82 10 44
Sequence references in MGI J:65296 Brouns MR, et al., The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development. 2000 Nov;127(22):4891-903
J:68904 Brouns MR, et al., p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7
J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137942 Jiang W, et al., p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration. J Biol Chem. 2008 Jul 25;283(30):20978-88
J:162994 Nemeth T, et al., Neutrophil Functions and Autoimmune Arthritis in the Absence of p190RhoGAP: Generation and Analysis of a Novel Null Mutation in Mice. J Immunol. 2010 Sep 1;185(5):3064-75
J:178482 Heckman-Stoddard BM, et al., P190A RhoGAP is required for mammary gland development. Dev Biol. 2011 Dec 1;360(1):1-10
J:232342 Stewart K, et al., A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects. PLoS Genet. 2016 Feb;12(2):e1005785
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory