Sequence Detail

ID/Version

Q91YL2 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase RNF126 {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:23418353};AltName: Full=RING finger protein 126 {ECO:0000312|MGI:MGI:1917544};

Provider

SWISS-PROT

Sequence

Polypeptide 313 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rnf126	ring finger protein 126	64	96	3	17

Sequence references in MGI

J:213100 Smith CJ, et al., The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor. J Cell Sci. 2013 Mar 15;126(Pt 6):1366-80
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:344817 Liu W, et al., RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy. Adv Sci (Weinh). 2023 Feb;10(5):e2203884