Sequence Detail

ID/Version

Q91YE3 Q8VHJ2 Q922P3 (UniProt | EBI)

Last sequence update: 2003-06-16
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Egl nine homolog 1; EC=1.14.11.29 {ECO:0000250|UniProtKB:Q9GZT9};AltName: Full=Hypoxia-inducible factor prolyl hydroxylase 2; Short=HIF-PH2; Short=HIF-prolyl hydroxylase 2; Short=HPH-2;AltName: Full=Prolyl hyd

Provider

SWISS-PROT

Sequence

Polypeptide 400 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Egln1	egl-9 family hypoxia-inducible factor 1	49	105	4	18

Sequence references in MGI

J:60099 Moschella MC, et al., SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation. Gene Expr. 1999;8(1):59-66
J:72041 Taylor MS, Characterization and comparative analysis of the EGLN gene family. Gene. 2001 Sep 5;275(1):125-32
J:132718 Minamishima YA, et al., Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure. Blood. 2008 Mar 15;111(6):3236-44
J:169844 Duan LJ, et al., Prolyl Hydroxylase Domain Protein 2 (PHD2) Mediates Oxygen-Induced Retinopathy in Neonatal Mice. Am J Pathol. 2011 Apr;178(4):1881-90
J:180457 Wu S, et al., Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene. Mol Ther. 2008 Jul;16(7):1227-34
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89