Sequence Detail

ID/Version

Q91Y44 G3X8Z8 Q59HJ4 (UniProt | EBI)

Last sequence update: 2012-11-28
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Bromodomain testis-specific protein;AltName: Full=Bromodomain-containing female sterile homeotic-like protein;AltName: Full=RING3-like protein;

Provider

SWISS-PROT

Sequence

Polypeptide 956 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Brdt	bromodomain, testis-specific	36	104	3	8

Sequence references in MGI

J:84555 Pivot-Pajot C, et al., Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. Mol Cell Biol. 2003 Aug;23(15):5354-65
J:128000 Shang E, et al., The first bromodomain of Brdt, a testis-specific member of the BET sub-family of double-bromodomain-containing proteins, is essential for male germ cell differentiation. Development. 2007 Oct;134(19):3507-15
J:178703 Berkovits BD, et al., The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background. Dev Biol. 2011 Dec 15;360(2):358-68
J:186056 Moriniere J, et al., Cooperative binding of two acetylation marks on a histone tail by a single bromodomain. Nature. 2009 Oct 1;461(7264):664-8
J:190041 Gaucher J, et al., Bromodomain-dependent stage-specific male genome programming by Brdt. EMBO J. 2012 Oct 3;31(19):3809-20
J:190257 Berkovits BD, et al., The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatids. Nucleic Acids Res. 2012 Aug;40(15):7162-75
J:243518 Goudarzi A, et al., Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters. Mol Cell. 2016 Apr 21;62(2):169-80
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89