Sequence Detail

ID/Version

Q91VN0 E9QQ75 Q9R208 O88883 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Low-density lipoprotein receptor-related protein 5 {ECO:0000303|PubMed:11956231}; Short=LRP-5;AltName: Full=Low-density lipoprotein receptor-related protein 7 {ECO:0000303|PubMed:10049586}; Short=LRP-7;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1614 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lrp5	low density lipoprotein receptor-related protein 5	99	121	4	38

Sequence references in MGI

J:49544 Hey PJ, et al., Cloning of a novel member of the low-density lipoprotein receptor family. Gene. 1998 Aug 17;216(1):103-11
J:53198 Chen D, et al., Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and human. Genomics. 1999 Feb 1;55(3):314-21
J:75973 Kato M, et al., Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol. 2002 Apr 15;157(2):303-14
J:82316 Hsieh JC, et al., Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity. Cell. 2003 Feb 7;112(3):355-67
J:91055 Kelly OG, et al., The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development. 2004 Jun;131(12):2803-15