Sequence Detail

ID/Version

Q91V92 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=ATP-citrate synthase; EC=2.3.3.8 {ECO:0000269|PubMed:25450640};AltName: Full=ATP-citrate (pro-S-)-lyase;AltName: Full=Citrate cleavage enzyme;

Provider

SWISS-PROT

Sequence

Polypeptide 1091 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acly	ATP citrate lyase	41	123	4	42

Sequence references in MGI

J:70827 Ehringer MA, et al., High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Mamm Genome. 2001 Aug;12(8):657-63
J:100999 Giannakopoulos NV, et al., Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:276384 Zhang H, et al., Enhanced lipid accumulation in the yeast Yarrowia lipolytica by over-expression of ATP:citrate lyase from Mus musculus. J Biotechnol. 2014 Dec 20;192 Pt A:78-84
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:316927 Tian M, et al., ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation. Elife. 2021 Sep 7;10:e62394