Sequence Detail

ID/Version

Q91V27 Q3UFV7 Q99N53 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Melanophilin;AltName: Full=Exophilin-3;AltName: Full=Leaden protein;AltName: Full=Slp homolog lacking C2 domains a; Short=SlaC2-a;AltName: Full=Synaptotagmin-like protein 2a;

Provider

SWISS-PROT

Sequence

Polypeptide 590 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mlph	melanophilin	34	100	4	12

Sequence references in MGI

J:69335 Fukuda M, et al., Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain. Biochem Biophys Res Commun. 2001 May 4;283(2):513-9
J:71302 Matesic LE, et al., Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10238-43
J:75876 Wu XS, et al., Identification of an organelle receptor for myosin-Va. Nat Cell Biol. 2002 Apr;4(4):271-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:155184 Kukimoto-Niino M, et al., Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure. 2008 Oct 8;16(10):1478-90
J:198812 Wei Z, et al., Structural basis of cargo recognitions for class V myosins. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11314-9