Sequence Detail

ID/Version

Q8VHQ2 Q3UH08 B1AQY1 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Suppressor of cytokine signaling 7 {ECO:0000305}; Short=SOCS-7 {ECO:0000303|PubMed:15242778};

Provider

SWISS-PROT

Sequence

Polypeptide 579 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Socs7	suppressor of cytokine signaling 7	25	99	3	18

Sequence references in MGI

J:77039 Krebs DL, et al., SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation. Mol Cell Biol. 2002 Jul;22(13):4567-78
J:93449 Krebs DL, et al., Development of hydrocephalus in mice lacking SOCS7. Proc Natl Acad Sci U S A. 2004 Nov 26;101(43):15446-51
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100915 Banks AS, et al., Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans. J Clin Invest. 2005 Sep;115(9):2462-71
J:205551 Simo S, et al., Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors. Dev Cell. 2013 Nov 25;27(4):399-411