Sequence Detail

ID/Version

Q8VHE6 Q8BWG1 E9QKD7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Dynein axonemal heavy chain 5 {ECO:0000305};AltName: Full=Axonemal beta dynein heavy chain 5; Short=mDNAH5;AltName: Full=Ciliary dynein heavy chain 5;

Provider

SWISS-PROT

Sequence

Polypeptide 4621 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dnah5	dynein, axonemal, heavy chain 5	63	100	3	23

Sequence references in MGI

J:76189 Ibanez-Tallon I, et al., Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Hum Mol Genet. 2002 Mar 15;11(6):715-21
J:92832 Ibanez-Tallon I, et al., Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum Mol Genet. 2004 Sep 15;13(18):2133-41
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:301033 Ide T, et al., CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components. PLoS Genet. 2020 Dec;16(12):e1009232