Sequence Detail

ID/Version

Q8VEK3 G3XA10 Q9R205 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Heterogeneous nuclear ribonucleoprotein U {ECO:0000312|MGI:MGI:1858195}; Short=hnRNP U {ECO:0000303|Ref.5};AltName: Full=Scaffold-attachment factor A {ECO:0000303|PubMed:18332112}; Short=SAF-A {ECO:0000303|PubMed:18332112};

Provider

SWISS-PROT

Sequence

Polypeptide 800 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hnrnpu	heterogeneous nuclear ribonucleoprotein U	256	100	4	11

Sequence references in MGI

J:98861 Roshon MJ, et al., Hypomorphic mutation in hnRNP U results in post-implantation lethality. Transgenic Res. 2005 Apr;14(2):179-92
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:136001 Onishi Y, et al., Rhythmic SAF-A binding underlies circadian transcription of the Bmal1 gene. Mol Cell Biol. 2008 May;28(10):3477-88
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:164278 Hasegawa Y, et al., The matrix protein hnRNP U is required for chromosomal localization of Xist RNA. Dev Cell. 2010 Sep 14;19(3):469-76
J:173042 Hara Y, et al., Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter. Nucleic Acids Res. 2009 Mar;37(4):1115-26
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:204641 Vizlin-Hodzic D, et al., SAF-A forms a complex with BRG1 and both components are required for RNA polymerase II mediated transcription. PLoS One. 2011;6(12):e28049
J:205556 Christophorou MA, et al., Citrullination regulates pluripotency and histone H1 binding to chromatin. Nature. 2014 Mar 6;507(7490):104-8
J:243396 Vizlin-Hodzic D, et al., SAF-A has a role in transcriptional regulation of Oct4 in ES cells through promoter binding. Cell Reprogram. 2011 Feb;13(1):13-27
J:243474 Yamada N, et al., Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome. PLoS Genet. 2015 Aug;11(8):e1005430
J:244072 Li S, et al., Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7111-E7120
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87