Sequence Detail

ID/Version

Q8VE98 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=CD276 antigen;AltName: Full=B7 homolog 3; Short=B7-H3;AltName: Full=Costimulatory molecule;AltName: CD_antigen=CD276;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 316 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd276	CD276 antigen	29	99	3	27

Sequence references in MGI

J:76926 Sun M, et al., Characterization of mouse and human B7-H3 genes. J Immunol. 2002 Jun 15;168(12):6294-7
J:84968 Ling V, et al., Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss. Genomics. 2003 Sep;82(3):365-77
J:84973 Suh WK, et al., The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses. Nat Immunol. 2003 Sep;4(9):899-906
J:85241 Sun X, et al., Mouse B7-H3 induces antitumor immunity. Gene Ther. 2003 Sep;10(20):1728-34
J:92691 Prasad DV, et al., Murine B7-H3 is a negative regulator of T cells. J Immunol. 2004 Aug 15;173(4):2500-6
J:95550 Wang L, et al., B7-H3 promotes acute and chronic allograft rejection. Eur J Immunol. 2005 Feb;35(2):428-438
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563