Sequence Detail

ID/Version

Q8VE47 Q9CYD6 Q3U9E7 Q3U8X9 Q3TG27 (UniProt | EBI)

Last sequence update: 2010-03-02
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ubiquitin-like modifier-activating enzyme 5 {ECO:0000305}; Short=Ubiquitin-activating enzyme 5 {ECO:0000303|PubMed:20018847};AltName: Full=UFM1-activating enzyme {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 403 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Uba5	ubiquitin-like modifier activating enzyme 5	60	98	3	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:158995 Tatsumi K, et al., A novel type of E3 ligase for the Ufm1 conjugation system. J Biol Chem. 2010 Feb 19;285(8):5417-27
J:289448 Tatsumi K, et al., The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice. Nat Commun. 2011 Feb 8;2:181
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:300137 Balce DR, et al., UFMylation inhibits the proinflammatory capacity of interferon-gamma-activated macrophages. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2011763118