Sequence Detail

ID/Version

Q8VDZ4 Q8R2X7 Q2TGE8 Q69ZB5 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Palmitoyltransferase ZDHHC5; EC=2.3.1.225 {ECO:0000269|PubMed:22081607, ECO:0000269|PubMed:24562000, ECO:0000269|PubMed:30605677};AltName: Full=Zinc finger DHHC domain-containing protein 5; Short=DHHC-5;

Provider

SWISS-PROT

Sequence

Polypeptide 715 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zdhhc5	zinc finger, DHHC domain containing 5	37	98	4	39

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:175999 Kokkola T, et al., Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 palmitoyltransferase. FEBS Lett. 2011 Sep 2;585(17):2665-70
J:212024 Brigidi GS, et al., Palmitoylation of delta-catenin by DHHC5 mediates activity-induced synapse plasticity. Nat Neurosci. 2014 Apr;17(4):522-32
J:270003 Li Y, et al., DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells. J Biol Chem. 2012 Jan 2;287(1):523-30
J:270005 Li Y, et al., DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory. J Biol Chem. 2010 Apr 23;285(17):13022-31
J:270120 Wang J, et al., DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep. 2019 Jan 2;26(1):209-221.e5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87