Sequence Detail

ID/Version

Q8VDP3 E9PXR1 Q3TBH9 Q3TX89 Q3TB77 D3Z4C6 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=[F-actin]-monooxygenase MICAL1 {ECO:0000305}; EC=1.14.13.225 {ECO:0000269|PubMed:23911929, ECO:0000269|PubMed:26935886}; EC=1.6.3.1 {ECO:0000250|UniProtKB:Q8TDZ2};AltName: Full=Molecule interacting with CasL protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 1048 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mical1	microtubule associated monooxygenase, calponin and LIM domain containing 1	69	96	3	14

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:175077 Zhou Y, et al., MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis. Mol Cell Biol. 2011 Sep;31(17):3603-15
J:200405 Yamamura R, et al., The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions. Mol Biol Cell. 2008 Mar;19(3):971-83
J:201326 Lee BC, et al., MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Mol Cell. 2013 Aug 8;51(3):397-404
J:240378 Van Battum EY, et al., The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections. Nat Commun. 2014 Jul 10;5:4317
J:266107 Alqassim SS, et al., Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights. Sci Rep. 2016 Mar 3;6:22176
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89