Sequence Detail

ID/Version

Q8VDL9 Q99P73 Q8R4X9 Q99MY6 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Zinc finger protein GLIS2;AltName: Full=GLI-similar 2;AltName: Full=Neuronal Krueppel-like protein;AltName: Full=Zinc finger protein GLI5;

Provider

SWISS-PROT

Sequence

Polypeptide 521 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Glis2	GLIS family zinc finger 2	48	102	4	110

Sequence references in MGI

J:67967 Lamar E, et al., Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation. Development. 2001 Apr;128(8):1335-46
J:75457 Zhang F, et al., Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis. J Biol Chem. 2002 Mar 22;277(12):10139-49
J:104117 Kim SC, et al., Kruppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1). Nucleic Acids Res. 2005;33(21):6805-15
J:127491 Hosking CR, et al., The transcriptional repressor Glis2 is a novel binding partner for p120 catenin. Mol Biol Cell. 2007 May;18(5):1918-27
J:176685 Li Binghua, et al., Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs. Hum Mol Genet. 2011 Nov 1;20(21):4155-66