Sequence Detail

ID/Version

Q8VCQ6 Q5J3R0 Q8C583 Q3UIS8 Q8C464 Q8C652 (UniProt | EBI)

Last sequence update: 2004-02-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phosphatidylcholine:ceramide cholinephosphotransferase 1; EC=2.7.8.27 {ECO:0000269|PubMed:27892528};AltName: Full=Protein Mob;AltName: Full=Sphingomyelin synthase 1;AltName: Full=Transmembrane protein 23;

Provider

SWISS-PROT

Sequence

Polypeptide 419 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sgms1	sphingomyelin synthase 1	47	101	4	426

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103447 Yang Z, et al., The mouse sphingomyelin synthase 1 (SMS1) gene is alternatively spliced to yield multiple transcripts and proteins. Gene. 2005 Dec 19;363:123-32
J:105120 Huitema K, et al., Identification of a family of animal sphingomyelin synthases. EMBO J. 2004 Jan 14;23(1):33-44
J:200056 Lu MH, et al., Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice. J Physiol. 2012 Aug 15;590(Pt 16):4029-44
J:201497 Li Z, et al., Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice. Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1577-84
J:220024 Ding T, et al., All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity. J Lipid Res. 2015 Mar;56(3):537-45
J:292436 Taniguchi M, et al., Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus. Sci Rep. 2016 Nov 28;6:37829