Sequence Detail

ID/Version

Q8VCN5 Q6H324 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Cystathionine gamma-lyase {ECO:0000303|PubMed:18948540, ECO:0000303|PubMed:19903941, ECO:0000303|PubMed:22244329, ECO:0000303|PubMed:33826201}; Short=CGL; Short=CSE {ECO:0000303|PubMed:18948540, ECO:0000303|PubMed:19903941, E

Provider

SWISS-PROT

Sequence

Polypeptide 398 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cth	cystathionine gamma lyase	48	104	4	21

Sequence references in MGI

J:91125 Ishii I, et al., Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. Biochem J. 2004 Jul 1;381(Pt 1):113-23
J:140705 Yang G, et al., H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science. 2008 Oct 24;322(5901):587-90
J:179897 Sen N, et al., Hydrogen Sulfide-Linked Sulfhydration of NF-kappaB Mediates Its Antiapoptotic Actions. Mol Cell. 2012 Jan 13;45(1):13-24
J:182483 Mustafa AK, et al., H2S signals through protein S-sulfhydration. Sci Signal. 2009;2(96):ra72
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:312261 Zhang Y, et al., Cystathionine gamma-lyase/H2 S signaling facilitates myogenesis under aging and injury condition. FASEB J. 2021 May;35(5):e21511