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Sequence Detail
ID/Version
Q8VCF0 (UniProt | EBI) Last sequence update: 2002-03-01
Last annotation update: 2019-10-16
Sequence
description
from provider
RecName: Full=Mitochondrial antiviral-signaling protein {ECO:0000305}; Short=MAVS {ECO:0000305};AltName: Full=CARD adapter inducing interferon beta; Short=Cardif;AltName: Full=Interferon beta promoter stimulator protein 1; Short=IP
Provider SWISS-PROT
Sequence
Polypeptide 503 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Mavs mitochondrial antiviral signaling protein 49 0 6 16
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:144594 Sanada T, et al., FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway. J Biol Chem. 2008 Dec 5;283(49):33858-64
J:257328 Liu Y, et al., The interaction between the helicase DHX33 and IPS-1 as a novel pathway to sense double-stranded RNA and RNA viruses in myeloid dendritic cells. Cell Mol Immunol. 2014 Jan;11(1):49-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory