Sequence Detail

ID/Version

Q8VBX6 Q9Z1K3 Q8VBV5 B7ZNA1 Q6P7U4 Q8C0H8 O08783 Q80ZY8 Q8BKJ1 Q8VBY0 (UniProt | EBI)

Last sequence update: 2005-06-21
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Multiple PDZ domain protein;AltName: Full=Multi-PDZ domain protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 2055 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mpdz	multiple PDZ domain crumbs cell polarity complex component	45	108	3	10

Sequence references in MGI

J:56256 Simpson EH, et al., Identification, sequence, and mapping of the mouse multiple PDZ domain protein gene, Mpdz. Genomics. 1999 Jul 1;59(1):102-4
J:73641 Hamazaki Y, et al., Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem. 2002 Jan 4;277(1):455-61
J:76251 Fehr C, et al., Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene. J Neurosci. 2002 May 1;22(9):3730-8
J:79970 Poliak S, et al., Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells. J Cell Biol. 2002 Oct 28;159(2):361-72
J:92068 Van De Pavert SA, et al., Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure. J Cell Sci. 2004 Aug 15;117(Pt 18):4169-77
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:163217 Ishiuchi T, et al., Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex. J Cell Biol. 2009 Jun 15;185(6):959-67
J:191149 Alves CH, et al., Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
J:218007 Mancini A, et al., The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity. FEBS Lett. 2000 Sep 29;482(1-2):54-8
J:225412 Wright GJ, et al., Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development. Development. 2004 Nov;131(22):5659-69
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87