Sequence Detail

ID/Version

Q8R4U7 Q9CSL6 A3KG96 Q8BQW1 Q3UV18 Q7TS71 Q99NG3 (UniProt | EBI)

Last sequence update: 2006-05-16
Last annotation update: 2025-04-09

Sequence description from provider

RecName: Full=Leucine zipper protein 1;AltName: Full=Filamin mechanobinding actin cross-linking protein {ECO:0000250|UniProtKB:Q86V48}; Short=Fimbacin {ECO:0000250|UniProtKB:Q86V48};AltName: Full=Leucine zipper motif-containing protein;

Provider

SWISS-PROT

Sequence

Polypeptide 1068 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Luzp1	leucine zipper protein 1	67	104	3	60

Sequence references in MGI

J:34242 Sun DS, et al., Identification, molecular characterization, and chromosomal localization of the cDNA encoding a novel leucine zipper motif-containing protein. Genomics. 1996 15;36(1):54-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:141306 Hsu CY, et al., LUZP deficiency affects neural tube closure during brain development. Biochem Biophys Res Commun. 2008 Nov 21;376(3):466-71
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:283453 Lee MW, et al., Restricted expression of LUZP in neural lineage cells: a study in embryonic stem cells. J Biomed Sci. 2001 Nov-Dec;8(6):504-11
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:305653 Yano T, et al., A microtubule-LUZP1 association around tight junction promotes epithelial cell apical constriction. EMBO J. 2021 Jan 15;40(2):e104712
J:355671 Bozal-Basterra L, et al., LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome. Elife. 2020 Jun 18;9
J:355672 Niri F, et al., Chromatin remodeling factor CECR2 forms tissue-specific complexes with CCAR2 and LUZP1. Biochem Cell Biol. 2021 Dec;99(6):759-765