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Sequence Detail
ID/Version
Q8R418 Q8R419 (UniProt | EBI) Last sequence update: 2009-09-01
Last annotation update: 2014-07-09
Sequence
description
from provider
RecName: Full=Endoribonuclease Dicer; EC=3.1.26.3;AltName: Full=Double-strand-specific ribonuclease mDCR-1;
Provider SWISS-PROT
Sequence
Polypeptide 1916 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Dicer1 dicer 1, ribonuclease type III 104 13 5 32
Sequence references in MGI J:74999 Nicholson RH, et al., Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference. Mamm Genome. 2002 Feb;13(2):67-73
J:92289 Doi N, et al., Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors. Curr Biol. 2003 Jan 8;13(1):41-6
J:132169 Du Z, et al., Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2391-6
J:203415 Flemr M, et al., A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes. Cell. 2013 Nov 7;155(4):807-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory