Sequence Detail

ID/Version

Q8R3U1 B7X6T3 Q8BWF7 Q3V3C3 (UniProt | EBI)

Last sequence update: 2005-04-26
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phospholipase A and acyltransferase 3 {ECO:0000250|UniProtKB:P53816}; EC=2.3.1.- {ECO:0000269|PubMed:19047760}; EC=3.1.1.32 {ECO:0000269|PubMed:18614531, ECO:0000269|PubMed:19047760, ECO:0000269|PubMed:19136964, ECO:0000269|P

Provider

SWISS-PROT

Sequence

Polypeptide 162 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plaat3	phospholipase A and acyltransferase 3	67	96	4	152

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:182487 Duncan RE, et al., Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA). J Biol Chem. 2008 Sep 12;283(37):25428-36
J:185104 Uyama T, et al., Regulation of peroxisomal lipid metabolism by catalytic activity of tumor suppressor H-rev107. J Biol Chem. 2012 Jan 20;287(4):2706-18
J:239202 Jaworski K, et al., AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency. Nat Med. 2009 Feb;15(2):159-68
J:239204 Uyama T, et al., The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type. J Lipid Res. 2009 Apr;50(4):685-93
J:244476 Staring J, et al., PLA2G16 represents a switch between entry and clearance of Picornaviridae. Nature. 2017 Jan 19;541(7637):412-416
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306889 Morishita H, et al., Organelle degradation in the lens by PLAAT phospholipases. Nature. 2021 Apr;592(7855):634-638
J:342638 Schuermans N, et al., Loss of phospholipase PLAAT3 causes a mixed lipodystrophic and neurological syndrome due to impaired PPARgamma signaling. Nat Genet. 2023 Nov;55(11):1929-1940