Sequence Detail

ID/Version

Q8R3H7 Q3TNP7 O88464 Q9JLK2 (UniProt | EBI)

Last sequence update: 2005-06-07
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Heparan sulfate 2-O-sulfotransferase 1; Short=2-O-sulfotransferase; Short=2-OST; Short=2OST; EC=2.8.2.- {ECO:0000269|PubMed:10677367};

Provider

SWISS-PROT

Sequence

Polypeptide 356 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hs2st1	heparan sulfate 2-O-sulfotransferase 1	19	101	4	10

Sequence references in MGI

J:48481 Bullock SL, et al., Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 1998 Jun 15;12(12):1894-906
J:71568 Merry CL, et al., The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse. J Biol Chem. 2001 Sep 21;276(38):35429-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:324199 Pinhal MA, et al., Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12984-9