Sequence Detail

ID/Version

Q8R307 Q8BZX6 Q8BGV6 Q8C126 (UniProt | EBI)

Last sequence update: 2004-06-07
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Vacuolar protein sorting-associated protein 18 homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 973 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vps18	VPS18 CORVET/HOPS core subunit	53	97	3	13

Sequence references in MGI

J:90042 Richardson SC, et al., Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. Mol Biol Cell. 2004 Mar;15(3):1197-210
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:185970 Peng C, et al., Vps18 deficiency inhibits dendritogenesis in Purkinje cells by blocking the lysosomal degradation of Lysyl Oxidase. Biochem Biophys Res Commun. 2012 Jul 13;423(4):715-20
J:186307 Peng C, et al., Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes. J Biol Chem. 2012 Sep 21;287(39):32861-73
J:222663 Perini ED, et al., Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations. Traffic. 2014 Dec;15(12):1366-89
J:222677 Zlatic SA, et al., Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells. Mol Biol Cell. 2011 May 15;22(10):1699-715
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89