Sequence Detail

ID/Version

Q8R2Z3 B1AWS0 A2AJZ4 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Anion exchange transporter;AltName: Full=Solute carrier family 26 member 7;

Provider

SWISS-PROT

Sequence

Polypeptide 656 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc26a7	solute carrier family 26, member 7	45	100	2	3

Sequence references in MGI

J:97085 Kim KH, et al., SLC26A7 is a Cl- channel regulated by intracellular pH. J Biol Chem. 2005 Feb 25;280(8):6463-70
J:131477 Petrovic S, et al., Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells. Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G1093-103
J:156969 Xu J, et al., Deletion of the chloride transporter slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion. J Biol Chem. 2009 Oct 23;284(43):29470-9
J:216082 Kim KX, et al., Slc26a7 chloride channel activity and localization in mouse Reissner's membrane epithelium. PLoS One. 2014;9(5):e97191
J:299446 Cao X, et al., SLC26A7 constitutes the thiocyanate-selective anion conductance of the basolateral membrane of the retinal pigment epithelium. Am J Physiol Cell Physiol. 2020 Oct 1;319(4):C641-C656
J:325346 Cangul H, et al., Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism. JCI Insight. 2018 Oct 18;3(20)
J:326785 Yamaguchi N, et al., The iodide transporter Slc26a7 impacts thyroid function more strongly than Slc26a4 in mice. Sci Rep. 2022 Jul 4;12(1):11259