Sequence Detail

ID/Version

Q8R2Z0 Q9CQI8 (UniProt | EBI)

Last sequence update: 2007-04-17
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Adipolin {ECO:0000303|PubMed:21849507};AltName: Full=Adipose-derived insulin-sensitizing factor {ECO:0000303|PubMed:21849507};AltName: Full=Complement C1q tumor necrosis factor-related protein 12;Contains: RecName: Full=Adipolin fC1QTNF12;

Provider

SWISS-PROT

Sequence

Polypeptide 308 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	C1qtnf12	C1q and tumor necrosis factor related 12	23	98	3	7

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:177588 Enomoto T, et al., Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism. J Biol Chem. 2011 Oct 7;286(40):34552-8
J:183116 Wei Z, et al., C1q/TNF-related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes. J Biol Chem. 2012 Mar 23;287(13):10301-15
J:185067 Seldin MM, et al., Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis. J Biol Chem. 2012 Apr 6;287(15):11968-80
J:208964 Bell-Anderson KS, et al., Loss of Kruppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2). Diabetes. 2013 Aug;62(8):2728-37
J:211140 Enomoto T, et al., Transcriptional regulation of an insulin-sensitizing adipokine adipolin/CTRP12 in adipocytes by Kruppel-like factor 15. PLoS One. 2013;8(12):e83183