Sequence Detail

ID/Version

Q8R2Q8 Q8CEY7 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Bone marrow stromal antigen 2; Short=BST-2;AltName: Full=HM1.24 antigen;AltName: CD_antigen=CD317;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 172 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bst2	bone marrow stromal cell antigen 2	57	98	2	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:139501 Blasius AL, et al., Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J Immunol. 2006 Sep 1;177(5):3260-5
J:180252 Liberatore RA, et al., Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18097-101
J:181846 Swiecki M, et al., Cutting Edge: Paradoxical Roles of BST2/Tetherin in Promoting Type I IFN Response and Viral Infection. J Immunol. 2012 Mar 15;188(6):2488-92
J:187543 Jones PH, et al., Bone marrow stromal cell antigen 2 (BST-2) restricts mouse mammary tumor virus (MMTV) replication in vivo. Retrovirology. 2012;9:10
J:187565 Radoshitzky SR, et al., Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin. J Virol. 2010 Oct;84(20):10569-80
J:190272 Sarojini S, et al., Interferon-induced tetherin restricts vesicular stomatitis virus release in neurons. DNA Cell Biol. 2011 Dec;30(12):965-74
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89