Sequence Detail

ID/Version

Q8R1I2 Q3UTL2 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Gastrin-releasing peptide; Short=GRP;Contains: RecName: Full=Neuromedin-C; AltName: Full=GRP-10; AltName: Full=GRP18-27 {ECO:0000303|PubMed:21933692};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 146 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Grp	gastrin releasing peptide	27	104	3	18

Sequence references in MGI

J:78753 Ladenheim EE, et al., Disruptions in feeding and body weight control in gastrin-releasing peptide receptor deficient mice. J Endocrinol. 2002 Aug;174(2):273-81
J:80849 Shumyatsky GP, et al., Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell. 2002 Dec 13;111(6):905-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:123810 Sun YG, et al., A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. Nature. 2007 Aug 9;448(7154):700-3
J:227985 Pereira PJ, et al., GRPR/PI3Kgamma: Partners in Central Transmission of Itch. J Neurosci. 2015 Dec 9;35(49):16272-81
J:229238 Li P, et al., The peptidergic control circuit for sighing. Nature. 2016 Feb 18;530(7590):293-7
J:240537 Yu YQ, et al., Molecular and neural basis of contagious itch behavior in mice. Science. 2017 Mar 10;355(6329):1072-1076
J:313601 Melzer S, et al., Bombesin-like peptide recruits disinhibitory cortical circuits and enhances fear memories. Cell. 2021 Oct 28;184(22):5622-5634.e25
J:320340 Andoh T, et al., Gastrin-releasing peptide induces itch-related responses through mast cell degranulation in mice. Peptides. 2011 Oct;32(10):2098-103