Sequence Detail

ID/Version

Q8R1B8 Q1MVR9 Q0PQZ3 Q0PQZ2 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Nuclear receptor ROR-beta;AltName: Full=Nuclear receptor RZR-beta;AltName: Full=Nuclear receptor subfamily 1 group F member 2;AltName: Full=Retinoid-related orphan receptor-beta;

Provider

SWISS-PROT

Sequence

Polypeptide 470 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rorb	RAR-related orphan receptor beta	39	134	3	28

Sequence references in MGI

J:48923 Andre E, et al., Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice. EMBO J. 1998 Jul 15;17(14):3867-77
J:111028 Srinivas M, et al., Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta. Mol Endocrinol. 2006 Aug;20(8):1728-41
J:121989 Masana MI, et al., Behavioral characterization and modulation of circadian rhythms by light and melatonin in C3H/HeN mice homozygous for the RORbeta knockout. Am J Physiol Regul Integr Comp Physiol. 2007 Jun;292(6):R2357-67
J:153683 Jia L, et al., Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17534-9
J:198114 Jabaudon D, et al., RORbeta induces barrel-like neuronal clusters in the developing neocortex. Cereb Cortex. 2012 May;22(5):996-1006
J:205743 Liu H, et al., An isoform of retinoid-related orphan receptor beta directs differentiation of retinal amacrine and horizontal interneurons. Nat Commun. 2013;4:1813
J:207072 Roforth MM, et al., Examination of nuclear receptor expression in osteoblasts reveals Rorbeta as an important regulator of osteogenesis. J Bone Miner Res. 2012 Apr;27(4):891-901