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Sequence Detail
ID/Version
Q8K4S1 Q3TS68 Q8BZF3 E9Q5G0 B9EHS1 Q80TC4 Q9JKM2 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 {ECO:0000305}; EC=3.1.4.11 {ECO:0000269|PubMed:12752375};AltName: Full=Phosphoinositide phospholipase C-epsilon-1;AltName: Full=Phospholipase C-epsilon-1; Sh
Provider SWISS-PROT
Sequence
Polypeptide 2282 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Plce1 phospholipase C, epsilon 1 40 99 3 20
Sequence references in MGI J:66491 Tidhar A, et al., A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells. Dev Dyn. 2001 Jan;220(1):60-73
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:84137 Wu D, et al., Neuronal lineage-specific induction of phospholipase Cepsilon expression in the developing mouse brain. Eur J Neurosci. 2003 Apr;17(8):1571-80
J:94952 Bai Y, et al., Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development. Cancer Res. 2004 Dec 15;64(24):8808-10
J:97661 Tadano M, et al., Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon. Mol Cell Biol. 2005 Mar;25(6):2191-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117556 Wang H, et al., Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy. Circ Res. 2005 Dec 9;97(12):1305-13
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory