Sequence Detail

ID/Version

Q8K4S1 E9Q5G0 Q8BZF3 Q9JKM2 Q80TC4 B9EHS1 Q3TS68 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 {ECO:0000305}; EC=3.1.4.11 {ECO:0000269|PubMed:12752375};AltName: Full=Phosphoinositide phospholipase C-epsilon-1;AltName: Full=Phospholipase C-epsilon-1; Sh

Provider

SWISS-PROT

Sequence

Polypeptide 2282 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plce1	phospholipase C, epsilon 1	24	102	3	20

Sequence references in MGI

J:66491 Tidhar A, et al., A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells. Dev Dyn. 2001 Jan;220(1):60-73
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:84137 Wu D, et al., Neuronal lineage-specific induction of phospholipase Cepsilon expression in the developing mouse brain. Eur J Neurosci. 2003 Apr;17(8):1571-80
J:94952 Bai Y, et al., Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development. Cancer Res. 2004 Dec 15;64(24):8808-10
J:97661 Tadano M, et al., Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon. Mol Cell Biol. 2005 Mar;25(6):2191-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117556 Wang H, et al., Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy. Circ Res. 2005 Dec 9;97(12):1305-13
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89