Sequence Detail

ID/Version

Q8K4G1 Q8K4G0 E9QPD9 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Latent-transforming growth factor beta-binding protein 4; Short=LTBP-4;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1666 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ltbp4	latent transforming growth factor beta binding protein 4	16	99	2	115

Sequence references in MGI

J:78819 Sterner-Kock A, et al., Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer. Genes Dev. 2002 Sep 1;16(17):2264-73
J:158211 Urban Z, et al., Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development. Am J Hum Genet. 2009 Nov;85(5):593-605
J:221200 Bultmann-Mellin I, et al., Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms. Dis Model Mech. 2015 Apr;8(4):403-15
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89