Sequence Detail

ID/Version

Q8K4C5 A6H6F0 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Interleukin-17C; Short=Il-17c;AltName: Full=Cytokine CX2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 194 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il17c	interleukin 17C	15	96	3	5

Sequence references in MGI

J:79437 Hurst SD, et al., New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J Immunol. 2002 Jul 1;169(1):443-53
J:177650 Chang SH, et al., Interleukin-17C Promotes Th17 Cell Responses and Autoimmune Disease via Interleukin-17 Receptor E. Immunity. 2011 Oct 28;35(4):611-21
J:178966 Song X, et al., IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat Immunol. 2011 Dec;12(12):1151-8
J:178967 Ramirez-Carrozzi V, et al., IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat Immunol. 2011 Dec;12(12):1159-66