Sequence Detail

ID/Version

Q8K348 A2AJR4 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Activin receptor type-1C; EC=2.7.11.30;AltName: Full=Activin receptor type IC; Short=ACTR-IC;AltName: Full=Activin receptor-like kinase 7; Short=ALK-7;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 493 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acvr1c	activin A receptor, type IC	89	105	2	12

Sequence references in MGI

J:94135 Jornvall H, et al., ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse. Mol Cell Biol. 2004 Nov;24(21):9383-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:136342 Bertolino P, et al., Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7246-51
J:351108 Lee ES, et al., Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors. J Biol Chem. 2022 Nov 18;299(1):102716