Sequence Detail

ID/Version

Q8K341 Q8C1D1 B8JJ75 Q8BM67 Q3UZR9 Q8K2M7 B8JJ77 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Alpha-tubulin N-acetyltransferase 1 {ECO:0000255|HAMAP-Rule:MF_03130}; Short=Alpha-TAT {ECO:0000255|HAMAP-Rule:MF_03130}; Short=Alpha-TAT1 {ECO:0000255|HAMAP-Rule:MF_03130}; Short=TAT {ECO:0000255|HAMAP-Rule:MF_03130}

Provider

SWISS-PROT

Sequence

Polypeptide 421 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atat1	alpha tubulin acetyltransferase 1	22	105	3	13

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:164738 Akella JS, et al., MEC-17 is an alpha-tubulin acetyltransferase. Nature. 2010 Sep 9;467(7312):218-22
J:201922 Kim GW, et al., Mice lacking alpha-tubulin acetyltransferase 1 are viable but display alpha-tubulin acetylation deficiency and dentate gyrus distortion. J Biol Chem. 2013 Jul 12;288(28):20334-50
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:205737 Kalebic N, et al., alphaTAT1 is the major alpha-tubulin acetyltransferase in mice. Nat Commun. 2013;4:1962
J:206083 Montagnac G, et al., alphaTAT1 catalyses microtubule acetylation at clathrin-coated pits. Nature. 2013 Oct 24;502(7472):567-70
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87