Sequence Detail

ID/Version

Q8K1T0 Q8VDE0 Q812A6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Transmembrane protease serine 3; EC=3.4.21.-;

Provider

SWISS-PROT

Sequence

Polypeptide 453 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tmprss3	transmembrane protease, serine 3	22	106	4	11

Sequence references in MGI

J:79978 Guipponi M, et al., The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro. Hum Mol Genet. 2002 Nov 1;11(23):2829-36
J:172676 Fasquelle L, et al., Tmprss3, a Transmembrane Serine Protease Deficient in Human DFNB8/10 Deafness, Is Critical for Cochlear Hair Cell Survival at the Onset of Hearing. J Biol Chem. 2011 May 13;286(19):17383-97