Sequence Detail

ID/Version

Q8K1G2 Q8BRF3 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Limbin;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1220 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Evc2	EvC ciliary complex subunit 2	12	104	2	17

Sequence references in MGI

J:78363 Takeda H, et al., Positional cloning of the gene LIMBIN responsible for bovine chondrodysplastic dwarfism. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10549-54
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:177234 Blair HJ, et al., Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus. BMC Biol. 2011;9:14
J:243385 Pusapati GV, et al., EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia. Dev Cell. 2014 Mar 10;28(5):483-96