Sequence Detail

ID/Version

Q8K1B8 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Fermitin family homolog 3;AltName: Full=Kindlin-3;AltName: Full=Unc-112-related protein 2;

Provider

SWISS-PROT

Sequence

Polypeptide 665 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fermt3	fermitin family member 3	30	106	3	14

Sequence references in MGI

J:114381 Ussar S, et al., The Kindlins: subcellular localization and expression during murine development. Exp Cell Res. 2006 Oct 1;312(16):3142-51
J:133659 Moser M, et al., Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med. 2008 Mar;14(3):325-30
J:145476 Kruger M, et al., SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell. 2008 Jul 25;134(2):353-64
J:146783 Moser M, et al., Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells. Nat Med. 2009 Mar;15(3):300-5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89