Sequence Detail

ID/Version

Q8K0V4 B2RUA7 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=CCR4-NOT transcription complex subunit 3;AltName: Full=CCR4-associated factor 3;

Provider

SWISS-PROT

Sequence

Polypeptide 751 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cnot3	CCR4-NOT transcription complex, subunit 3	27	105	4	36

Sequence references in MGI

J:157579 Suzuki A, et al., NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9
J:180033 Morita M, et al., Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice. EMBO J. 2011 Nov 16;30(22):4678-91
J:196241 Zheng X, et al., Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation. Stem Cells. 2012 May;30(5):910-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:307831 Minegishi K, et al., Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex. Nat Commun. 2021 Jul 1;12(1):4071