Sequence Detail

ID/Version

Q8K0H1 Q9CQ64 Q5SS45 (UniProt | EBI)

Last sequence update: 2007-12-04
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Multidrug and toxin extrusion protein 1; Short=MATE-1; Short=mMATE-1;AltName: Full=Solute carrier family 47 member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 567 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc47a1	solute carrier family 47, member 1	27	102	8	17

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:163959 Tsuda M, et al., Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin. Mol Pharmacol. 2009 Jun;75(6):1280-6
J:212164 Chen L, et al., OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9983-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:328825 Hiasa M, et al., Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations. Am J Physiol Cell Physiol. 2006 Oct;291(4):C678-86