Sequence Detail

ID/Version

Q8K0C4 Q9JIY3 Q9JIP8 Q8BSQ7 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Lanosterol 14-alpha demethylase {ECO:0000303|PubMed:10864439, ECO:0000303|PubMed:21705796}; Short=LDM; EC=1.14.14.154 {ECO:0000269|PubMed:21705796};AltName: Full=CYPLI;AltName: Full=Cytochrome P450 51A1; Short=CYP51 {

Provider

SWISS-PROT

Sequence

Polypeptide 503 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cyp51	cytochrome P450, family 51	11	118	3	6

Sequence references in MGI

J:63000 Debeljak N, et al., Characterization of the mouse lanosterol 14alpha-demethylase (CYP51), a new member of the evolutionarily most conserved cytochrome P450 family. Arch Biochem Biophys. 2000 Jul 1;379(1):37-45
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:173366 Keber R, et al., Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome. J Biol Chem. 2011 Aug 19;286(33):29086-97
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89