Sequence Detail

ID/Version

Q8JZR6 Q9JKV6 Q3TAV7 Q8BYI7 Q6A004 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Electroneutral sodium bicarbonate exchanger 1;AltName: Full=Electroneutral Na+-driven Cl-HCO3 exchanger;AltName: Full=Solute carrier family 4 member 8;AltName: Full=k-NBC3;

Provider

SWISS-PROT

Sequence

Polypeptide 1089 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc4a8	solute carrier family 4 (anion exchanger), member 8	102	100	3	12

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:136047 Chen LM, et al., Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNS. Neuroscience. 2008 Apr 22;153(1):162-74
J:161474 Leviel F, et al., The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. J Clin Invest. 2010 May 3;120(5):1627-35
J:173358 Sinning A, et al., Synaptic glutamate release is modulated by the Na+ -driven Cl-/HCO3- exchanger Slc4a8. J Neurosci. 2011 May 18;31(20):7300-11
J:328865 Xu J, et al., Slc4a8 in the Kidney: Expression, Subcellular Localization and Role in Salt Reabsorption. Cell Physiol Biochem. 2018;50(4):1361-1375