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Sequence Detail
ID/Version
Q8CJ27 Q8BJI8 B1ARM7 Q8BKT4 O88482 Q4G1G9 A0A0G2JES1 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Abnormal spindle-like microcephaly-associated protein homolog;AltName: Full=Calmodulin-binding protein Sha1; Short=Calmodulin-binding protein 1;AltName: Full=Spindle and hydroxyurea checkpoint abnormal protein;
Provider SWISS-PROT
Sequence
Polypeptide 3122 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Aspm abnormal spindle microtubule assembly 41 109 3 20
Sequence references in MGI J:51919 Craig R, et al., The novel murine calmodulin-binding protein Sha1 disrupts mitotic spindle and replication checkpoint functions in fission yeast. J Cell Sci. 1998 Dec 18;111(Pt 24):3609-19
J:79525 Luers GH, et al., Murine calmodulin binding protein 1 (Calmbp1): tissue-specific expression during development and in adult tissues. Mech Dev. 2002 Oct;118(1-2):229-32
J:79564 Bond J, et al., ASPM is a major determinant of cerebral cortical size. Nat Genet. 2002 Oct;32(2):316-20
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100395 Kouprina N, et al., The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein. Hum Mol Genet. 2005 Aug 1;14(15):2155-65
J:242409 Jiang K, et al., Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex. Nat Cell Biol. 2017 May;19(5):480-492

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory