Sequence Detail

ID/Version

Q8CJ12 A2AHQ0 A2AHP9 Q8CJ08 Q8CJ09 Q8CJ10 Q8BL10 A2AHQ3 A2AHP8 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Adhesion G-protein coupled receptor G2 {ECO:0000305};AltName: Full=G-protein coupled receptor 64 {ECO:0000303|PubMed:18469038};AltName: Full=Mouse epididymis-specific protein 6 {ECO:0000303|PubMed:12420295}; Short=Me6 {ECO:0000303|Pu

Provider

SWISS-PROT

Sequence

Polypeptide 1009 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adgrg2	adhesion G protein-coupled receptor G2	35	99	3	14

Sequence references in MGI

J:80477 Obermann H, et al., HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia. Mol Reprod Dev. 2003 Jan;64(1):13-26
J:93019 Davies B, et al., Targeted deletion of the epididymal receptor HE6 results in fluid dysregulation and male infertility. Mol Cell Biol. 2004 Oct;24(19):8642-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:145661 Kirchhoff C, et al., HE6/GPR64 adhesion receptor co-localizes with apical and subapical F-actin scaffold in male excurrent duct epithelia. Reproduction. 2008 Aug;136(2):235-45
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:362039 Xiao P, et al., Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature. 2022 Apr;604(7907):771-778
J:362041 Lin H, et al., Structures of the ADGRG2-G(s) complex in apo and ligand-bound forms. Nat Chem Biol. 2022 Nov;18(11):1196-1203