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Sequence Detail
ID/Version
Q8CIR4 A0A1W5LU38 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Transient receptor potential cation channel subfamily M member 6; EC=2.7.11.1 {ECO:0000269|PubMed:28821869};AltName: Full=Channel kinase 2;AltName: Full=Melastatin-related TRP cation channel 6;Contains: RecName: Full=TRPM6 kinase, c
Provider SWISS-PROT
Sequence
Polypeptide 2028 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Trpm6 transient receptor potential cation channel, subfamily M, member 6 52 106 3 9
Sequence references in MGI J:153718 Walder RY, et al., Mice defective in Trpm6 show embryonic mortality and neural tube defects. Hum Mol Genet. 2009 Nov 15;18(22):4367-75
J:239386 Chubanov V, et al., Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife. 2016 Dec 19;5:e20914
J:355633 Ferioli S, et al., TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg(2+) and Mg.ATP. Sci Rep. 2017 Aug 18;7(1):8806

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory